- Ultem Publications Inc. - Short lived Golden Age publisher.
- Ultracomics - imprint of Harvey Comics.
- Undercurrent (1994) - 402 West Garner Road, Garner, NC 27529.
- United Features Syndicate - Golden Age publisher of comic strip reprints.
- United Publications - British anthropomorphic b/w publisher.
- Upton, Colin (1994) - 6424 Chester, Vancouver, B.C., V5W 3C3, CANADA.
- U.S.A. Comics - Publisher of comic strip reprints in the mid-1980's.
- U.S. Manga (1994) - 250 West 57th St, Suite #317, NY, NY 10107. 1-800-MANGA-77.
- U.S. Consumer Product Safety Commission (CPSC) - Ocassionally publishes informational comic books.
- Utterly Strange Publications - Short lived b/w publisher of the early 1990s.